Chairman and Founder, SomaLogic
Professor of Molecular, Cellular and Developmental Biology
University of Colorado Boulder
The Gold lab began with basic research on bacteria and bacteriophage, then shifted focus to human disease following the invention of the SELEX process in 1989. SELEX (Systematic Evolution of Ligands by Exponential enrichment) is a combinatorial chemistry methodology in which vast numbers of oligonucleotides (DNA, RNA, or unnatural compounds) are screened rapidly for specific sequences that have appropriate binding affinities and specificities toward any target. SELEX also has been used to identify new ribozymes and deoxyribozymes. The Gold Lab currently focuses on the utilization of biological and information technology to improve healthcare.