Elliot T. and Onie H. Adams Professor of Biochemistry and Systems Biology
Harvard Medical School
Pamela Silver received her BS in Chemistry and PhD in Biochemistry from the University of California. She was a Postdoctoral Fellow at Harvard University where she was a Fellow of the American Cancer Society and The Medical Foundation. Subsequently, she was an Assistant Professor in the Dept of Molecular Biology at Princeton University where she was an Established Investigator of the American Heart Association, a Research Scholar of the March of Dimes and was awarded an NSF Presidential Young Investigator Award. She moved to Harvard Medical School where she was a Professor in the Dept of Biological Chemistry and Molecular Pharmacology where she was named a Claudia Adams Barr Investigator. She subsequently moved to the newly formed Department of Systems Biology, and was the first Director of the Harvard University PhD Program in Systems Biology and one of the first members of the Harvard University Wyss Institute for Biologically Inspired Engineering. She has been a Fellow of The Radcliffe Institute and was named the Elliot T and Onie H Adams Professor of Biochemistry and Systems Biology at Harvard. She has served on numerous boards and was a co-founder of Karyopharm Therapeutics (NASDAQ:KPTI) that makes novel anti-cancer drugs. In her free time, she enjoys sailboat racing and running - she has competed in several Boston Marathons and co-won the Marblehead Racing Association One Design Series.
"Design at the Interface of Biology and Chemistry"
Chemistry and Biology offer an array of complementary design strategies. Chemists can produce molecules that act as catalysts and materials used in electronics, energy capture and just about everything we do. Biology rivals Chemistry in making responders to environmental signals, harvesting of energy to make complex molecules and the ability to self-replicate. Here, I discuss attempts to integrate the features of both. In doing so, we design biologically-based computation, a chemical-biological hybrid bionic leaf, and biological factories programmed to carry out complex chemistry.